pentobarbital will lower the extent or influence of aripiprazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
pentobarbital will decrease the extent or impact of lonafarnib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Lonafarnib is really a delicate CYP3A4 substrate. Coadministration with strong or average CYP3A4 inducers is contraindicated.
pentobarbital will decrease the level or impact of tacrolimus by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
pentobarbital will minimize the extent or result of pantoprazole by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Unidentified.
pentobarbital will minimize the extent or influence of carbamazepine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
pentobarbital will minimize the extent or effect of triamcinolone acetonide injectable suspension by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
CYP3A4 inducers could enhance the formation from the neurotoxic/nephrotoxic ifosfamide metabolite, chloroacetaldehyde. Carefully watch people taking ifosfamide with CYP3A4 inducers for toxicities and consider dose adjustment.
pentobarbital will decrease the extent or impact of dasatinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
Contraindicated (1)pentobarbital will lessen the extent or impact of doravirine by impacting hepatic/intestinal enzyme CYP3A4 metabolism.
Therapy should get more info be administered with warning, if in any way, to sufferers who're mentally frustrated, have suicidal tendencies, or heritage of drug abuse
Data are now not accessible to Assess effect of barbiturates when forceps supply or other intervention is critical; also, data are not accessible to ascertain the result of these barbiturates to the later advancement, growth, and functional maturation of the kid
pentobarbital will reduce the extent or impact of atorvastatin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
With therapeutic doses of TCAs, barbiturates improve metabolism and decrease blood concentrations of TCAs.
Comment: Barbiturates may possibly maximize adverse effects, including respiratory depression, produced by toxic doses of TCAs. With therapeutic doses of TCAs, barbiturates boost metabolism and decrease blood concentrations of TCAs.